Lab on a chip 2017 Backcover

Lab on a chip 2017 Backcover

An encoded viral micropatch for multiplex cellbased assays through localized gene delivery The increasing number of potential drug targets and compounds has led to the development of highthroughput cell-based assays. Simultaneous processing of multiple targets in the same experiment based on localized target gene expression is a very efficient strategy for this purpose. To address this need, we present an adenoviral vector-immobilized microparticle with two-dimensional (2D) shape-encoding properties that allows localized patch-like gene delivery to monolayer-cultured cells. This format conveniently achieves multiplexed gene delivery compatible with both high-throughput cellular assays and fluorescence high-content imaging instruments. A multiplex G protein-coupled receptor (GPCR) internalization assay was developed to demonstrate the compatibility of this system with high-throughput image-based cellular assays.

"Self-organization of maze-like structures via guided wrinkling" Science advances (2017)

Sophisticated three-dimensional (3D) structures found in nature are self-organized by bottom-up natural processes. To artificially construct these complex systems, various bottom-up fabrication methods, designed to transform 2D structures into 3D structures, have been developed as alternatives to conventional top-down lithography processes. We present a different self-organization approach, where we construct microstructures with periodic and ordered, but with random architecture, like mazes. For this purpose, we transformed planar surfaces using wrinkling to directly use randomly generated ridges as maze walls. Highly regular maze structures, consisting of several tessellations with customized designs, were fabricated by precisely controlling wrinkling with the ridge-guiding structure, analogous to the creases in origami. The method presented here could have widespread applications in various material systems with multiple length scales.
Advanced Materials 2015 Cover

Advanced Materials 2015 Cover

An unclonable, fingerprint-mimicking anti-counterfeiting strategy is presented that encrypts polymeric particles with randomly generated silica film wrinkles. The generated wrinkle codes are as highly unique as human fingerprints and are technically irreproducible. Superior to previous physical unclonable functions, codes are tunable on demand and generable on various geometries. Reliable authentication of real-world products that have these microfingerprints is demonstrated using optical decoding methods.

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Advanced Materials 2012 Cover

Advanced Materials 2012 Cover

A QR-coded microtaggant for the anti-counterfeiting of drugs is proposed that can provide high capacity and error-correction capability. It is fabricated lithographically in a microfluidic channel with special consideration of the island patterns in the QR Code. The microtaggant is incorporated in the drug capsule (“on-dose authentication”) and can be read by a simple smartphone QR Code reader application when removed from the capsule and washed free of drug.

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Nature materials 2008 Cover

Nature materials 2008 Cover

Fluidic self-assembly is a promising pathway for parallel fabrication of devices made up of many small components. Here, we introduce 'railed microfluidics' as an agile method to guide and assemble microstructures inside fluidic channels. The guided movement of microstructures in microfluidic channels was achieved by fabricating grooves ('rails') on the top surface of the channels and also creating complementary polymeric microstructures that fit with the grooves. Using the rails as a guiding mechanism, we built complex one- and two-dimensional microsystems in which all the microstructures initially involved in the fabrication method were incorporated as components in the final product. Complex structures composed of more than 50 microstructures (each sized smaller than 50 mum) were fluidically self-assembled with zero error. Furthermore, we were able to use the rails to guide microstructures through different fluid solutions, successfully overcoming strong interfacial tension between solutions. On the basis of rail-guided self-assembly and cross-solution movement, we demonstrated heterogeneous fluidic self-assembly of polymeric microstructures and living cells. In addition to such assembly of in situ polymerized structures, we also guided and assembled externally fabricated silicon chips—demonstrating the feasible application of railed microfluidics to other materials systems.

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Introduced in discover magazine

Introduced in discover magazine

http://blogs.discovermagazine.com/d-brief/2017/07/03/mini-mazes-could-serve-as-cybersecurity-moats/#more-20221

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과학과 기술 - 새해, 과학기술계에 바란다 기고

새해, 과학기술계에 바란다 (원본링크

상상력이 미래의 경쟁력이다

상은 언제나 현실을 앞선다. 1970~80년대 007시리즈나 TV 시리즈물이었던 전격 Z작전 같은 영화에서는 주인공이 그 시절 상상하지 못했던 첨단 무기들을 들고 나와 단숨에 적을 제압하고 영화는 행복한 결론으로 끝난다. 기억나는 첨단 장비는 초소형 무선송수신기, 귓속에 넣어놓고 주인공을 지원하는 기지의 어여쁜 조력자의 도움을 받는다. 도주하는 적의 옷 혹은 자동차에 작은 크기의 위치 추적장치를 달아 놓고, 미행하여 급습한다.

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2013년 2학기 물리전자 강의실 변경 217호 -> 227호

2013년도 2학기 물리전자 수업 강의실이 변경되었습니다. 생체의공학과 최성용 교수님께서 배려를 해주셨습니다.

9월 6일 금요일부터 227호에서 뵙도록 하겠습니다.

강의실 변경으로 오늘 수업시간에 학번과 이름을 적어주신분들 명단을 학과에 제출하도록 하겠습니다. 

감사합니다.

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QR Coded microtaggent for anti-counterfeit drug

http://news.kbs.co.kr/science/2012/11/23/2572088.html

<앵커 멘트>

가짜 발기부전 치료제 등 위조약은 약효 문제뿐 아니라 심각한 부작용을 불러올 수 있습니다.

의약품 낱알에 미세한 식별 기호를 새겨넣어 정품 확인이 가능한 기술이 기술이 개발됐습니다.

신방실 기자가 취재했습니다.

<리포트>

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인턴 학생 및 대학원 입학 지원자 모집

인턴학생및대학원입학지원자를모집합니다.

20세기전자공학은눈부신발전을거듭하였습니다. 우리의삶은송두리채바꿔놓고있습니다. 제가어릴적공상과학영화속에나나오는통신장치들은이젠더이상영화속의허구가아닙니다. 단지몇년전의상상이었지만, 이제는현실이며그상상과현실의거리는점점줄어들고있습니다.

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